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Valproic acid sodium salt (Sodium valproate)
SPC-02320
CAS No. 1069-66-5
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
HDAC inhibitor ; GABA Receptor inhibitor ; PGC-1α activator ; Mitophagy activator ; Autophagy activator ; Notch activator
| Description |
|---|
| Valproic acid sodium salt (Sodium valproate) is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1069-66-5 |
| Description | Valproic acid sodium salt (Sodium valproate) is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. |
| Formula | C8H15NaO2 |
| Molecular Weight | 166.19 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | N/A |
| SMILES | CCCC(CCC)C(=O)[O-].[Na+] |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.