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TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody
SPA-10727
| Size | Price |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | THRB |
| Gene Abbr. | THRB |
| Gene ID | 7068 |
| Full Name | thyroid hormone receptor beta |
| Alias | C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2 |
| Introduction | Thyroid Hormone Receptor beta (TR beta, THRB; NR1A2) is a member of the Nuclear Hormone Receptor superfamily. The ligands for TR beta are the thyroid hormones, which exist in two forms: T4 (3,5,3',5'-tetraiodo-L-thyronine) and T3 (3,5,3'-tri-iodo-L-thyronine). TR beta plays critical roles in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the Retinoid X Receptors (RXRs), which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of TR. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | H3825A |
| Isotype | IgG2A |
| Immunogen | Recombinant human TR beta 1/NR1A2. aa 2-100. |
| Usage | |
|---|---|
| Application | WB, IP, ELISA |
| Reactivity | Human |
| Specificity | This antibody specifically recognizes human TR beta 1, and does not cross-react with human TR beta 2 or human TR alpha. Not yet tested in other species. |
| Storage & Handling | |
|---|---|
| Storage Buffer | A liquid formulation in physiologic saline with 0.1% NaN3. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.