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Sunitinib
SPC-02107
CAS No. 557795-19-4
| Size | Price |
| 50 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PDGFR inhibitor ; c-Kit inhibitor ; VEGFR inhibitor ; IRE1 inhibitor ; Autophagy activator ; Apoptosis related activator
| Description |
|---|
| Sunitinib (SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1α. Sunitinib induces autophagy and apoptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 557795-19-4 |
| Description | Sunitinib (SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1α. Sunitinib induces autophagy and apoptosis. |
| Formula | C22H27FN4O2 |
| Molecular Weight | 398.47 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | SU11248 |
| SMILES | CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.