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SOST/Sclerostin Antibody
SPA-09869
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Sclerostin |
| Gene Abbr. | SOST |
| Gene ID | 50964 |
| Full Name | sclerostin |
| Alias | CDD, DAND6, SOST1, VBCH |
| Introduction | SOST, also known as sclerostin, belongs to the Cerberus/DAN family of secreted glycoproteins. SOST binds BMP-5, -6, and -7 with high affinity and BMP-2 and -4 with low affinity and functions in bone homeostasis as a BMP antagonist. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse SOST/Sclerostin. Gln24-Tyr211. Accession # NP_077769. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (2 µg/mL); Immunohistochemistry (5-15 µg/mL) |
| Reactivity | Mouse |
| Specificity | Detects mouse SOST/Sclerostin in direct ELISAs and Western Blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human SOST is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.