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SHMT1 Antibody
SPA-09984
| Size | Price |
| 100 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | SHMT1 |
| Gene Abbr. | SHMT1 |
| Gene ID | 6470 |
| Full Name | serine hydroxymethyltransferase 1 |
| Alias | CSHMT, SHMT |
| Introduction | This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | The immunogen this antibody was made to, maps to a region between residue 453 to 483 of human Serine Hydroxymethyltransferase 1 using the numbering given in entry NP_004160.3 (GeneID 6470). |
| Usage | |
|---|---|
| Application | WB, ELISA, IHC, IP |
| Dilutions | Western Blot (1:500-1:2500); ELISA (1:100-1:2000); Immunohistochemistry (1:500-1:2000); Immunoprecipitation (2-10 μg/mg lysate) |
| Reactivity | Human, Mouse, Primate-Orangutan |
| Storage & Handling | |
|---|---|
| Storage Buffer | Tris-Citrate/Phosphate (pH 7.0-8.0). |
| Preservative | 0.09% Sodium Azide |
| Storage Temp. | Store at 4 °C. |
| Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.