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SF-1/NR5A1/Steroidogenic Factor 1 Antibody
SPA-09920
| Size | Price |
| 100 µL | Online Inquiry |
| 20 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | SF-1/NR5A1 |
| Gene Abbr. | NR5A1 |
| Gene ID | 2516 |
| Full Name | nuclear receptor subfamily 5 group A member 1 |
| Alias | AD4BP, ELP, FTZ1, FTZF1, POF7 |
| Introduction | Streroidogenic Factor 1 (SF-1, AD4BP, FTZ-F1; NR5A1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development, including the hypothalamic-pituitary-gonadal axis and sex determination. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic 17 aa peptide from near C-terminus of human SF-1/NR5A1/Steroidogenic Factor 1. |
| Usage | |
|---|---|
| Application | IHC |
| Dilutions | Immunohistochemistry (2.5-5 µg/mL) |
| Reactivity | Human, Mouse, Rat, Bovine, Canine, Hamster, Primate, Rabbit |
| Specificity | Human NR5A1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.