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SF-1/NR5A1/Steroidogenic Factor 1 Antibody
SPA-09917
| Size | Price |
| 100 µL | Online Inquiry |
| 20 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | SF-1/NR5A1 |
| Gene Abbr. | NR5A1 |
| Gene ID | 2516 |
| Full Name | nuclear receptor subfamily 5 group A member 1 |
| Alias | AD4BP, ELP, FTZ1, FTZF1, POF7 |
| Introduction | Streroidogenic Factor 1 (SF-1, AD4BP, FTZ-F1; NR5A1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development, including the hypothalamic-pituitary-gonadal axis and sex determination. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | OTI1B4 |
| Isotype | IgG2A |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-262 of human NR5A1(NP_004950) produced in E.coli. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (1:2000); Immunohistochemistry (1:150) |
| Reactivity | Human |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS (pH 7.3), 1.0% BSA and 50% Glycerol. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.