Serpin A7/TBG Antibody - CD BioSciences

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Serpin A7/TBG Antibody

Serpin A7/TBG Antibody

SPA-09902

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0.1 mL Online Inquiry
0.025 mL Online Inquiry
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Target Information
Target Name Serpin A7/TBG
Gene Abbr. SERPINA7
Gene ID 6906
Full Name serpin family A member 7
Alias TBG, TBGQTL
Introduction Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Produced in rabbits immunized with purified, recombinant Mouse Serpin A7/TBG (NP_808588.3; Met 1-Gln 418).
Usage
Application ELISA
Reactivity Mouse
Storage & Handling
Storage Buffer 0.2 µm filtered solution in PBS.
Preservative No Preservative
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

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