SAR131675 - CD BioSciences

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SAR131675

SAR131675

SPC-01948

SAR131675

CAS No. 1433953-83-3

Size Price
10 mM (1 mL in DMSO) Online Inquiry
10 mg Online Inquiry
50 mg Online Inquiry
Bulk Size Online Inquiry

VEGFR inhibitor

Description
SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.
Product Details
CAS No. CAS No. 1433953-83-3
Description SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.
Formula C18H22N4O4
Molecular Weight 358.39
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#CC(C)(COC)O)C(=O)NC)N
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.