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SAR131675
SPC-01948

CAS No. 1433953-83-3
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
10 mg | Online Inquiry |
50 mg | Online Inquiry |
Bulk Size | Online Inquiry |
VEGFR inhibitor
Description |
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SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc. |
Product Details | |
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CAS No. | CAS No. 1433953-83-3 |
Description | SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc. |
Formula | C18H22N4O4 |
Molecular Weight | 358.39 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#CC(C)(COC)O)C(=O)NC)N |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.