RGM-B Antibody - CD BioSciences

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RGM-B Antibody

RGM-B Antibody

SPA-09581

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Target Information
Target Name RGM-B
Gene Abbr. RGMB
Gene ID 285704
Full Name repulsive guidance molecule BMP co-receptor b
Alias DRAGON
Introduction RGM-B, also known as DRAGON, is a 40 kDa member of the repulsive guidance molecule (RGM) family of GPI-linked neuronal and muscle membrane proteins. It is synthesized as a preproprotein that consists of a 48 amino acid (aa) signal sequence, a 367 aa mature region, and a 21 aa C-terminal prosegment. RGM-B contains two potential N-linked glycosylation sites and an abbreviated von Willebrand factor domain.
Product Details
Host Sheep
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse RGM-B. Gly49-Ser414. Accession # Q7TQ33.
Usage
Application WB, FC, IHC
Dilutions Western Blot (0.1 µg/mL); Flow Cytometry (2.5 µg/10^6 cells); Immunohistochemistry (5-15 µg/mL)
Reactivity Mouse
Specificity Detects mouse RGM-B in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, less than 5% cross-reactivity with recombinant mouse (rm) RGM-A and rmRGM-C is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.