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Phospho-Talin (Ser425) Antibody
SPA-10571
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Talin |
| Gene Abbr. | TLN1 |
| Gene ID | 7094 |
| Full Name | talin 1 |
| Alias | ILWEQ, TLN, talin-1 |
| Introduction | Focal adhesions connect the cytoskeleton with the extracellular matrix. Talin is a large, multidomain focal adhesion protein that interacts with the intracellular domains of integrins and other focal adhesion proteins. Talin is involved in the formation of focal adhesions and in linking focal adhesions to the actin cytoskeleton. The interaction between talin and integrins increases the affinity between integrin and both insoluble and soluble ECM proteins. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | D2P2M |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding Ser425 of human talin protein. |
| Source/Purification | Antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser425 of human talin protein. |
| Usage | |
|---|---|
| Application | WB, IP |
| Dilutions | Western Blot (1:1000); Immunoprecipitation (1:50) |
| MW(KDa) | 270 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Sensitivity | Endogenous |
| Specificity | It recognizes endogenous levels of talin protein only when phosphorylated at Ser425. Based on sequence homology, this antibody is expected to recognize both talin-1 and talin-2 proteins phosphorylated at Ser425. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. |
| Preservative | Less than 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Do not aliquot the antibody. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.