Phospho-Acetyl-CoA Carboxylase (Ser79) Sandwich ELISA Kit - CD BioSciences

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Phospho-Acetyl-CoA Carboxylase (Ser79) Sandwich ELISA Kit

Phospho-Acetyl-CoA Carboxylase (Ser79) Sandwich ELISA Kit

SPK-00023

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Target Information
Target Name ACC
Gene Abbr. ACACA
Gene ID 31
Full Name acetyl-CoA carboxylase
Alias ACAC, ACACAD, ACC, ACC1, ACCA
Introduction Acetyl-CoA carboxylase (ACC) catalyzes the carboxylation of acetyl-CoA to malonyl-CoA. It is the key enzyme in the biosynthesis and oxidation of fatty acids. In rodents, the 265 kDa ACC1 (ACCα) form is primarily expressed in lipogenic tissues, while 280 kDa ACC2 (ACCβ) is the main isoform in oxidative tissues. However, in humans, ACC2 is the predominant isoform in both lipogenic and oxidative tissues. Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC. ACC is a potential target of anti-obesity drugs.
Product Details
Measurement Sandwich
Usage
Application ELISA
Reactivity
Sensitivity This kit detects endogenous levels of ACC protein when phosphorylated at Ser79.

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