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Pentraxin 3/TSG-14 Antibody
SPA-08772
Size | Price |
0.1 mg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | Pentraxin 3 |
Gene Abbr. | PTX3 |
Gene ID | 5806 |
Full Name | pentraxin 3 |
Alias | TNFAIP5, TSG-14 |
Introduction | Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta. |
Product Details | |
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Host | Mouse |
Clonality | Monoclonal |
Clone No. | PPJ0069 |
Isotype | IgG2A |
Usage | |
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Application | WB, ELISA |
Reactivity | Human |
Storage & Handling | |
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Storage Buffer | A liquid formulation in physiologic saline with 0.1% NaN3. |
Preservative | 0.1% Sodium Azide |
Storage Temp. | Store the unopened product at -70 °C. Do not use past expiration date. |
Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.