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PAR2 Antibody
SPA-08587
| Size | Price |
| 0.1 mg | Online Inquiry |
| 0.025 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | PAR2 |
| Gene Abbr. | F2RL1 |
| Gene ID | 2150 |
| Full Name | F2R like trypsin receptor 1 |
| Alias | GPR11, PAR2 |
| Introduction | The Proteinase-activated receptor 2 (PAR2) is a member of the proteinase-activated receptor subfamily. It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases. This is in contrast to other members of the subfamily which are activated by the protease thrombin. PAR2 has been implicated in acute inflammatory response, asthma, and pain transmission. PAR2 expression has been documented in the periphery. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic peptide taken within amino acid region 300-370 of mouse PAR2. |
| Usage | |
|---|---|
| Application | WB, ELISA, IHC, IP |
| Dilutions | Western Blot (1:250); ELISA (1:1500-1:20000); Immunohistochemistry (1:100); Immunoprecipitation (1:200) |
| Reactivity | Human, Mouse, Rat, Primate |
| Specificity | This antibody detects a band of approximately 50kDa PAR2 protein in samples and a 52kDa protein in rat hippocampal samples. The antibody also labels a faint band of 110kDa in hippocampal membranes, probably represents either an uncharacterized variant of PAR2 or a non-specific protein. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Tris/Glycine buffer, pH 7.4-7.8, HEPES, BSA 0.5%, glycerol 30% . |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.