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P2Y12/P2RY12 Antibody
SPA-08360
| Size | Price |
| 0.1 mg | Online Inquiry |
| 0.025 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | P2Y12 |
| Gene Abbr. | P2RY12 |
| Gene ID | 64805 |
| Full Name | purinergic receptor P2Y12 |
| Alias | ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R |
| Introduction | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic peptide selected from human P2Y12 receptor gene corresponding to amino acids with the 320-342 at the C-terminus of protein. The peptide was covalently modified to achieve desired antigenicity before coupling to a carrier protein. |
| Usage | |
|---|---|
| Application | WB, ELISA, IF, IHC, IP |
| Dilutions | Western Blot (1:500); ELISA (1:10000); Immunofluorescence (1:100); Immunohistochemistry (1:100); Immunoprecipitation (1:200) |
| Reactivity | Human, Mouse, Rat, Porcine, Primate |
| Specificity | This antibody detects a single 56-68kDa P2Y12 diffused band. The antibody does not cross reacts with other P2X or with other P2Y receptors on Western Blots. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Tris/Glycine buffer, pH 7.4-7.8, HEPES, BSA 0.5%, glycerol 30% . |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.