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P2X7/P2RX7 Antibody
SPA-08356
| Size | Price |
| 0.1 mL | Online Inquiry |
| 0.025 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | P2X6 |
| Gene Abbr. | P2RX7 |
| Gene ID | 5027 |
| Full Name | purinergic receptor P2X 7 |
| Alias | P2X7 |
| Introduction | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Peptide with sequence YETNKVTRIQSMNY-C corresponding to N-Terminus according to NP_002553.2. |
| Usage | |
|---|---|
| Application | WB, IHC, ELISA |
| Dilutions | Western Blot (1-3 µg/mL); Immunohistochemistry (3-6 µg/mL); ELISA (1:16000) |
| Reactivity | Human, Mouse, Rat, Canine |
| Storage & Handling | |
|---|---|
| Storage Buffer | Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.