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P2X7/P2RX7 Antibody
SPA-08355
| Size | Price |
| 0.1 mL | Online Inquiry |
| 0.025 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | P2X6 |
| Gene Abbr. | P2RX7 |
| Gene ID | 5027 |
| Full Name | purinergic receptor P2X 7 |
| Alias | P2X7 |
| Introduction | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | A synthetic peptide from the extracellular domain of mouse P2X7 (P2RX7, P2X purinoceptor 7, Purinergic receptor, P2Z receptor, ATP receptor) conjugated to an immunogenic carrier protein was used as the immunogen. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (1:300-1:2000); Immunohistochemistry (1:10-1:500) |
| Reactivity | Human, Mouse, Rat, Primate |
| Storage & Handling | |
|---|---|
| Storage Buffer | Whole antisera. |
| Preservative | No Preservative |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.