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NFAT5 Antibody
SPA-08081
| Size | Price |
| 50 µg | Online Inquiry |
| 25 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | NFAT5 |
| Gene Abbr. | NFAT5 |
| Gene ID | 10725 |
| Full Name | nuclear factor of activated T cells 5 |
| Alias | NF-AT5, NFATL1, NFATZ, OREBP, TONEBP |
| Introduction | The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic peptide corresponding to residues C D(1439) L L V S L Q N Q G N N L T G S F(1455) of human NFAT5. |
| Usage | |
|---|---|
| Application | WB, ChIP, IF, IHC, IP |
| Dilutions | Western Blot (1:1000); Chromatin Immunoprecipitation (1:10-1:500); Immunohistochemistry (1:20); Immunoprecipitation (3 μg) |
| Reactivity | Human, Mouse, Rat, Canine, Hamster, Rabbit |
| Validation | Knockdown Validated. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS with 1 mg/mL BSA. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.