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MuSK Antibody
SPA-07768
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | MuSK |
| Gene Abbr. | MUSK |
| Gene ID | 4593 |
| Full Name | muscle associated receptor tyrosine kinase |
| Alias | CMS9, FADS, FADS1 |
| Introduction | Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM] |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Recombinant protein containing residues 210-304 from the extracellular domain of rat MuSK. |
| Usage | |
|---|---|
| Application | WB, IF, IHC, IP |
| Dilutions | Western Blot (1:500-1:1000); Immunofluorescence (1:20-1:100); Immunohistochemistry (1:20-1:100); Immunoprecipitation (1:10-1:500) |
| Reactivity | Human, Mouse, Rat |
| Specificity | Detects MUSK from mouse and rat tissue samples as well as COS7 cells transfected with rat MUSK. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS with 1 mg/mL BSA and 30% glycerol. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.