MUL1 Antibody - CD BioSciences

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MUL1 Antibody

MUL1 Antibody

SPA-07754

Size Price
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100 µg Online Inquiry
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Target Information
Target Name MUL1
Gene Abbr. MUL1
Gene ID 79594
Full Name mitochondrial E3 ubiquitin protein ligase 1
Alias C1orf166, GIDE, MAPL, MULAN, RNF218
Introduction MUL1 is an E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, MUL1 activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 5H6.2D5
Isotype IgG1 Kappa
Immunogen Partial recombinant protein made to a C-terminal portion of the human MUL1 protein (between residues 200-352) [UniProt Q969V5].
Usage
Application WB, IHC
Dilutions Immunohistochemistry (5 µg/mL)
Reactivity Human, Primate
Storage & Handling
Storage Buffer PBS.
Preservative 0.05% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.