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mGluR3 Antibody
SPA-07553
| Size | Price |
| 0.05 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | mGluR |
| Gene Abbr. | GRM3 |
| Gene ID | 2913 |
| Full Name | glutamate metabotropic receptor 3 |
| Alias | GLUR3, GPRC1C, MGLUR3, mGlu3 |
| Introduction | The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM3 / MGLUR3. |
| Usage | |
|---|---|
| Application | WB, IHC, IF |
| Dilutions | Western Blot (1:100-1:2000); Immunohistochemistry (5-10 µg/mL); Immunofluorescence (1:10-1:500) |
| Reactivity | Human, Porcine, Bovine, Equine, Primate, Mouse, Rat, Primate-Orangutan, Rabbit |
| Specificity | Human mGluR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.