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mGluR2 Antibody
SPA-07551
| Size | Price |
| 0.05 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | mGluR |
| Gene Abbr. | GRM2 |
| Gene ID | 2912 |
| Full Name | glutamate metabotropic receptor 2 |
| Alias | GLUR2, GPRC1B, MGLUR2, mGlu2 |
| Introduction | The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GRM2 / MGLUR2. |
| Usage | |
|---|---|
| Application | WB, IHC, IF |
| Dilutions | Western Blot (1:100-1:2000); Immunofluorescence (1:10-1:500) |
| Reactivity | Human, Mouse, Rat, Porcine, Bovine, Canine, Hamster, Rabbit, Equine, Primate |
| Specificity | Human mGluR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM3 (42%). |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.