Melatonin R1A/MT1/MTNR1A Antibody - CD BioSciences

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Melatonin R1A/MT1/MTNR1A Antibody

Melatonin R1A/MT1/MTNR1A Antibody

SPA-07731

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Target Information
Target Name MTNR1A
Gene Abbr. MTNR1A
Gene ID 4543
Full Name melatonin receptor 1A
Alias MEL-1A-R, MT1
Introduction This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 281-350 of human Melatonin R1A/MT1/MTNR1A (NP_005949.1).
Usage
Application WB, IHC
Dilutions Western Blot (1:500-1:2000); Immunohistochemistry (1:100-1:200)
Reactivity Human, Mouse, Rat
Storage & Handling
Storage Buffer PBS with 50% glycerol, pH 7.3.
Preservative 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Avoid freeze-thaw cycles.

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