MAML1 Antibody - CD BioSciences

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MAML1 Antibody

MAML1 Antibody

SPA-07167

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Target Information
Target Name MAML1
Gene Abbr. MAML1
Gene ID 9794
Full Name mastermind like transcriptional coactivator 1
Alias Mam-1, Mam1
Introduction Mastermind-like (MAML) family of proteins are homologs of Drosophila Mastermind. The family is composed of three members in mammals: MAML1, MAML2, and MAML3. MAML proteins form complexes with the intracellular domain of Notch (ICN) and the transcription factor CSL (RBP-Jκ) to regulate Notch target gene expression. MAML1 also interacts with myocyte enhancer factor 2C (MEF2C) to regulate myogenesis. MAML2 is frequently found to be fused with Mucoepidermoid carcinoma translocated gene 1 (MECT1, also know as WAMTP1 or TORC1) in patients with mucoepidermoid carcinomas and Warthin's tumors.
Product Details
Host Rabbit
Clonality Monoclonal
Clone No. D3K7B
Immunogen Synthetic peptide corresponding to residues surrounding Asp269 of human MAML1 protein.
Source/Purification Antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp269 of human MAML1 protein.
Usage
Application WB, IP, ChIP
Dilutions Western Blot (1:1000); Immunoprecipitation (1:200)
MW(KDa) 130
Reactivity Human, Mouse, Rat
Sensitivity Endogenous
Specificity It recognizes endogenous levels of total MAML1 protein. This antibody does not detect MAML2 or MAML3.
Storage & Handling
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide.
Preservative Less than 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Do not aliquot the antibody.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.