Lysyl Oxidase Homolog 2/LOXL2 Antibody - CD BioSciences

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Lysyl Oxidase Homolog 2/LOXL2 Antibody

Lysyl Oxidase Homolog 2/LOXL2 Antibody

SPA-07116

Size Price
0.1 mL Online Inquiry
0.025 mL Online Inquiry
More Options Online Inquiry
Target Information
Target Name Lysyl Oxidase Like
Gene Abbr. LOXL2
Gene ID 4017
Full Name lysyl oxidase like 2
Alias LOR, LOR2, WS9-14
Introduction This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Synthetic peptides corresponding to the C terminal of Loxl2. Immunizing peptide sequence NNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYYDLLSLNGTKVAEGHKA. The peptide sequence for this immunogen was taken from within the described region.
Usage
Application WB
Dilutions Western Blot (1:100-1:2000)
Reactivity Mouse, Human, Rat, Bovine, Canine, Equine, Guinea Pig, Rabbit
Storage & Handling
Storage Buffer PBS and 2% Sucrose.
Preservative 0.09% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Avoid freeze-thaw cycles.

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