Lysyl Oxidase Homolog 2/LOXL2 Antibody - CD BioSciences

service-banner

Lysyl Oxidase Homolog 2/LOXL2 Antibody

Lysyl Oxidase Homolog 2/LOXL2 Antibody

SPA-07115

Size Price
0.1 mL Online Inquiry
0.025 mL Online Inquiry
More Options Online Inquiry
Target Information
Target Name Lysyl Oxidase Like
Gene Abbr. LOXL2
Gene ID 4017
Full Name lysyl oxidase like 2
Alias LOR, LOR2, WS9-14
Introduction This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 3C5
Isotype IgG2B Kappa
Immunogen LOXL2 (NP_002309, 675 a.a. ~ 773 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSP.
Usage
Application WB, ELISA
Dilutions Western Blot (1:500); ELISA (1:100-1:2000)
Reactivity Human
Specificity LOXL2 - lysyl oxidase-like 2.
Storage & Handling
Storage Buffer In 1X PBS, pH 7.4.
Preservative No Preservative
Storage Temp. Aliquot and store at -20 °C or -80 °C.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.