Lysyl Oxidase Homolog 2/LOXL2 Antibody - CD BioSciences

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Lysyl Oxidase Homolog 2/LOXL2 Antibody

Lysyl Oxidase Homolog 2/LOXL2 Antibody

SPA-07114

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0.1 mL Online Inquiry
0.025 mL Online Inquiry
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Target Information
Target Name Lysyl Oxidase Like
Gene Abbr. LOXL2
Gene ID 4017
Full Name lysyl oxidase like 2
Alias LOR, LOR2, WS9-14
Introduction This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 262418
Isotype IgG2B
Immunogen Mouse myeloma cell line NS0-derived recombinant human Lysyl Oxidase Homolog 2/LOXL2. Gln26-Gln744 (predicted).
Usage
Application WB, IP
Dilutions Western Blot (1 µg/mL); Immunoprecipitation (25 µg/mL)
Reactivity Human
Specificity Detects human Lysyl Oxidase Homolog 2/LOXL2 in direct ELISAs and Western Blots.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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