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Lysyl Oxidase Homolog 2/LOXL2 Antibody
SPA-07113
Size | Price |
0.1 mL | Online Inquiry |
0.025 mL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | Lysyl Oxidase Like |
Gene Abbr. | LOXL2 |
Gene ID | 4017 |
Full Name | lysyl oxidase like 2 |
Alias | LOR, LOR2, WS9-14 |
Introduction | This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq] |
Product Details | |
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Host | Mouse |
Clonality | Monoclonal |
Clone No. | 5D2 |
Isotype | IgG2B Kappa |
Immunogen | LOXL2 (NP_002309, 675 a.a. ~ 773 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSP. |
Usage | |
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Application | WB, ELISA, IF, IHC |
Dilutions | Western Blot (1:500) |
Reactivity | Human, Mouse |
Specificity | LOXL2 - lysyl oxidase-like 2. |
Storage & Handling | |
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Storage Buffer | In 1X PBS, pH 7.4. |
Preservative | No Preservative |
Storage Temp. | Aliquot and store at -20 °C or -80 °C. |
Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.