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Lymphotoxin-alpha/TNF-beta Antibody
SPA-07099
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Lymphotoxin alpha |
| Gene Abbr. | LTA |
| Gene ID | 4049 |
| Full Name | lymphotoxin alpha |
| Alias | LT, TNFB, TNFSF1, TNLG1E |
| Introduction | Lymphotoxin alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | E. coli-derived recombinant human Lymphotoxin‑ alpha /TNF‑ beta. Leu35-Leu205. P01374. |
| Usage | |
|---|---|
| Application | WB |
| Dilutions | Western Blot (1 µg/mL); Neutralization (0.2-0.4 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human Lymphotoxin‑ alpha /TNF‑ beta in direct ELISAs and Western Blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human TNF-alpha and recombinant mouse TNF-alpha is observed. Neutralizes the biological activity of recombinant human (rh) TNF-beta and natural human TNF-beta, but will not neutralize the biological activity of rhTNF-alpha or recombinant mouse TNF-alpha. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.