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LXR beta/NR1H2 Antibody
SPA-08200
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | NR1H2/LXR |
| Gene Abbr. | NR1H2 |
| Gene ID | 7376 |
| Full Name | nuclear receptor subfamily 1 group H member 2 |
| Alias | LXR-b, LXRB, NER, NER-I, RIP15 |
| Introduction | Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous. The corresponding gene for the LXR beta is NR1H2. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Peptide with sequence SSPTTSSLDTPLPGC corresponding to N-Terminus according to NP_009052.3. |
| Usage | |
|---|---|
| Application | FC, IF, ELISA |
| Dilutions | Flow Cytometry (10 µg/mL); Immunofluorescence (10 µg/mL); ELISA (1:28000) |
| Reactivity | Human, Mouse, Rat, Canine |
| Specificity | Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.