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Laminin alpha 4 Antibody
SPA-06880
| Size | Price |
| 0.1 mL | Online Inquiry |
| 25 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Laminin |
| Gene Abbr. | LAMA4 |
| Gene ID | 3910 |
| Full Name | laminin subunit alpha 4 |
| Alias | CMD1JJ, LAMA3, LAMA4*-1 |
| Introduction | Laminins are heterotrimeric glycoproteins and are major components of the basement membrane. Each laminin is comprised of a single alpha, beta, and gamma chain that heterotrimerize via their coiled-coil domains to form a large cruciform-shaped molecule. Mature Laminin alpha 4 is a subunit of Laminin 411, Laminin 421, and Laminin 423. Mature Laminin alpha 4 is a 1792 amino acid (aa) residue protein that has a Laminin N-terminal domain, four Laminin EGF-like domains, the coiled-coil domain, and five C‑terminal tandem Laminin G-like domains. The G-like domains contain binding sites for integrin, heparin, and dystroglycan. Within the region used as immunogen, mouse Laminin alpha 4 shows 91% and 97% aa sequence identity with human and rat Laminin alpha 4, respectively. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 839084 |
| Isotype | IgG1 |
| Immunogen | Chinese hamster ovary cell line CHO-derived recombinant human Laminin alpha 4. Arg826-Ser1816. Accession # Q16363. |
| Usage | |
|---|---|
| Application | IF |
| Dilutions | Immunofluorescence (8-25 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human Laminin alpha 4 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Laminin alpha 4 or recombinant human Laminin alpha 3 is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.