IL-36 alpha/IL-1F6 Antibody - CD BioSciences

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IL-36 alpha/IL-1F6 Antibody

IL-36 alpha/IL-1F6 Antibody

SPA-05897

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Target Information
Target Name IL-36
Gene Abbr. IL36A
Gene ID 27179
Full Name interleukin 36 alpha
Alias FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON)
Introduction Human interleukin 1 family member #6 [IL-1F6; also Interleukin-36 alpha, IL36A, FIL-1 epsilon (epsilon)] is a member of the IL-1 family of proteins. IL-1 family members include IL-1 beta, IL-1 alpha, IL‑1ra, IL-18 and IL-1F5 through F10. All family members show a 12 beta -strand, beta -trefoil configuration, and all family members are believed to have arisen from a common ancestral gene that has undergone multiple duplications. IL-1F6 is synthesized as a 158 amino acid (aa) protein that contains no signal sequence, no prosegment and no potential N-linked glycosylation site(s). It appears to be actively secreted. When found in cell lysate, it presents as an 18 kDa monomer.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen An 11 amino acid peptide near the carboxy terminus of human IL-36A. The immunogen is located within the last 50 amino acids of IL-36A. Amino Acid Squence: AELGKANTTDFG.
Usage
Application WB, ELISA, IF, IHC
Dilutions Western Blot (1-2 µg/mL); Immunofluorescence (20 µg/mL)
Reactivity Human
Specificity IL-36A antibody is human specific. IL-36A antibody will not cross-react with IL-36B or IL-36G.
Storage & Handling
Storage Buffer PBS.
Preservative 0.02% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

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