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IL-28R alpha/IFN-lambda R1 Antibody
SPA-06487
Size | Price |
0.1 mL | Online Inquiry |
25 µL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | Interferon Receptor |
Gene Abbr. | IFNLR1 |
Gene ID | 163702 |
Full Name | interferon lambda receptor 1 |
Alias | CRF2/12, IFNLR, IL-28R1, IL28RA, LICR2 |
Introduction | IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain. |
Product Details | |
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Host | Goat |
Clonality | Polyclonal |
Clone No. | N/A |
Isotype | IgG |
Immunogen | Synthetic peptide: LPGLGSPPNVTYFVTYQSYIKTGWRPVEH, corresponding to N terminal amino acids 44-72 of Mouse IL28 Receptor alpha. |
Usage | |
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Application | ELISA, FC, IHC |
Dilutions | ELISA (1:50000); Flow Cytometry (1:10); Immunohistochemistry (1:150) |
Reactivity | Mouse, Rat |
Specificity | This recognizes the N-terminus of mouse CRF-2-12 (IL-28 receptor alpha) protein. This is likely to recognize rat CRF-2-12 (IL-28 receptor alpha) protein due to sequence similiarity. The peptide sequence is < 50 % identical to other sequences in GenBank. |
Storage & Handling | |
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Storage Buffer | 10 mM KHPO4, 0.14 M NaCl and 1.0 mg/mL BSA. |
Preservative | 0.1% Sodium Azide |
Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.