IFN-gamma R2 Antibody - CD BioSciences

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IFN-gamma R2 Antibody

IFN-gamma R2 Antibody

SPA-06482

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Target Information
Target Name Interferon Receptor
Gene Abbr. IFNGR2
Gene ID 3460
Full Name interferon gamma receptor 2
Alias AF-1, IFGR2, IFNGT1, IMD28
Introduction This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq]
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant human IFN-gamma R2. Ala22-Gln247. Accession # P38484.
Usage
Application WB, FC
Dilutions Western Blot (0.1 µg/mL); Flow Cytometry (2.5 µg/10^6 cells); Neutralization (0.5-2.5 µg/mL)
Reactivity Human
Specificity Detects human IFN-gamma R2 in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, less than 1% cross‑reactivity with recombinant human IFN‑ gamma R1 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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