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FXR/NR1H4 Antibody
SPA-08213
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | NR1H4/FXR |
| Gene Abbr. | NR1H4 |
| Gene ID | 9971 |
| Full Name | nuclear receptor subfamily 1 group H member 4 |
| Alias | BAR, FXR, HRR-1, HRR1, PFIC5 |
| Introduction | FXR is a 56 kDa nuclear receptor belonging to the NR1 subfamily. It is highly expressed in liver, intestine, kidney and white adipose tissue. FXR binds bile acids and functions as a transcription activator or repressor through interactions with a large variety of FXR response elements. Human and mouse FXR share approximately 92% amino acid sequence identity. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | A9033A |
| Isotype | IgG2A |
| Immunogen | Recombinant human FXR/NR1H4. aa 2-126. |
| Usage | |
|---|---|
| Application | WB, IHC, IP, ELISA |
| Reactivity | Human |
| Specificity | This antibody specifically recognizes human FXR and cross-reacts with rat and mouse FXR. Not yet tested in other species. |
| Storage & Handling | |
|---|---|
| Storage Buffer | A liquid formulation in physiologic saline with 0.1% NaN3. |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.