FAK Antibody - CD BioSciences

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FAK Antibody

FAK Antibody

SPA-03772

Size Price
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100 µg Online Inquiry
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Target Information
Target Name FAK
Gene Abbr. PTK2
Gene ID 5747
Full Name protein tyrosine kinase 2
Alias FADK, FAK, FAK1, FRNK, PPP1R71
Introduction Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival. Activation of FAK by integrin clustering leads to autophosphorylation at Tyr397, which is a binding site for the Src family kinases PI3K and PLCγ. Recruitment of Src family kinases results in the phosphorylation of Tyr407, Tyr576, and Tyr577 in the catalytic domain, and Tyr871 and Tyr925 in the carboxy-terminal region of FAK.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 10H7E9
Isotype IgG1
Immunogen Purified recombinant fragment of human FAK expressed in E. coli.
Usage
Application WB, ELISA, FC, IF
Dilutions Western Blot (1:500-1:2000); ELISA (1:10000); Flow Cytometry (1:200-1:400); Immunofluorescence (1:200-1:1000)
MW(KDa) 125
Reactivity Human
Storage & Handling
Storage Buffer Ascites.
Preservative 0.03% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.