ERp57 Antibody - CD BioSciences

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ERp57 Antibody

ERp57 Antibody

SPA-03690

Size Price
25 µg Online Inquiry
100 µg Online Inquiry
More Options Online Inquiry
Target Information
Target Name ERp57
Gene Abbr. PDIA3
Gene ID 2923
Full Name protein disulfide isomerase family A member 3
Alias ER60, ERp57, ERp60, ERp61, GRP57
Introduction Secretory proteins translocate into the endoplasmic reticulum (ER) after their synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds. This process is called oxidative protein folding. Disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds. Other ER resident proteins that possess the thioredoxin homology domains, including endoplasmic reticulum stress protein 57 (ERp57), constitute the PDI family. ERp57 interacts with calnexin and calreticulin and is suggested to play a role in the isomerization of disulfide bonds on certain glycoproteins.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Recombinant protein encompassing a sequence within the center region of human ERp57.
Usage
Application WB, IF, IHC
Dilutions Western Blot (1:500-1:10000); Immunofluorescence (1:100-1:1000); Immunohistochemistry (1:100-1:1000)
MW(KDa) 57
Reactivity Human, Mouse, Rat, Porcine, Bovine, Primate, Rabbit, Rhesus Macaque, Sheep
Storage & Handling
Storage Buffer PBS (pH 7), 20% Glycerol, 1% BSA.
Preservative 0.01% Thimerosal
Storage Temp. Aliquot and store at -20 °C or -80 °C.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.