eEF1A1 Antibody - CD BioSciences

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eEF1A1 Antibody

eEF1A1 Antibody

SPA-03229

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100 µg Online Inquiry
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Target Information
Target Name eEF1A
Gene Abbr. EEF1A1
Gene ID 1915
Full Name eukaryotic translation elongation factor 1 alpha 1
Alias CCS-3, CCS3, EE1A1, EEF-1, EEF1A
Introduction Translation is the process where amino acid residues are assembled into polypeptides on ribosomes. This process is generally divided into three stages: initiation, elongation and termination. During elongation, mRNA and tRNA pair at the two active sites (A and P sites) on the ribosome. A number of eukaryotic elongation factors (eEFs) are involved in this process in mammalian cells. eEF1A, also called elongation factor Tu (EF-Tu), binds GTP and interacts with amino acyl-tRNAs to promote recruitment of amino acyl-tRNAs to the A-site of the ribosome. After GTP hydrolysis, GDP-eEF1A leaves the ribosome and is later converted back to the GTP-eEF1A by eEF1B. Studies have shown that eEF1A is phosphorylated under certain conditions, indicating that its activity is regulated at the post-translational level.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 123-462 of human EEF1A1 (NP_001393.1).
Usage
Application WB, IF
MW(KDa) 50
Reactivity Human, Mouse, Rat
Storage & Handling
Storage Buffer PBS with 50% glycerol, pH 7.3.
Preservative 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.