CXCR4 Antibody - CD BioSciences

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CXCR4 Antibody

CXCR4 Antibody

SPA-02560

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Target Information
Target Name CXCR4
Gene Abbr. CXCR4
Gene ID 7852
Full Name C-X-C motif chemokine receptor 4
Alias CD184, D2S201E, FB22, HM89, HSY3RR
Introduction CXCR4 is a chemokine receptor that belongs to the G protein-coupled receptor family. It is activated by a small cytokine, CXCL12, also known as stromal cell derived factor 1 (SDF-1). The main function of CXCR4 is the mediation of the homing of progenitor cells in the bone marrow and their recruitment to sites of injury. More recently, CXCR4 has been studied, as a potential therapeutic target, in the context of autoimmune diseases as well as cancer, as the receptor is involved in the regulation of migration, proliferation, and survival of cancer cells.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Rabbit anti-CXCR4 polyclonal A peptide corresponding to amino acids 328-338 of human CXCR4.
Usage
Application WB, IF, IHC
Dilutions Western Blot (1-2 µg/mL); Immunohistochemistry (1:10-1:500)
MW(KDa) 45-60
Reactivity Human, Mouse, Rat, Sheep
Validation Knockdown Validated.
Specificity In HeLa, a 45 kDa band is observed.
Storage & Handling
Storage Buffer PBS.
Preservative 0.05% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.