Online Inquiry
CXCL17/VCC-1 Antibody
SPA-02512
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CXCL17 |
| Gene Abbr. | CXCL17 |
| Gene ID | 284340 |
| Full Name | C-X-C motif chemokine ligand 17 |
| Alias | DMC, Dcip1, UNQ473, VCC-1, VCC1 |
| Introduction | CXCL17, also known as dendritic cell and monocyte chemokine-like protein (DMC) and VEGF-correlated chemokine-1 (VCC-1), is a secreted molecule with a size and predicted three-dimensional folding pattern similar to that of chemokines CXCL8/IL-8 and CXCL14/BRAK. It has no predicted N-glycosylation site. Cleavage of a 23 amino acid (aa) signal sequence yields the mature 96 aa human CXCL17. CXCL17 is constitutively produced by airway and intestinal epithelium. It induces the chemotaxis of quiescent, but not LPS-activated peripheral blood monocytes and dendritic cells. CXCL17 expression is increased in endothelial cells when they are induced to form tubes in vitro. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 422208 |
| Isotype | IgG2B |
| Immunogen | E. coli-derived recombinant human CXCL17/VCC‑1. Leu24-Leu119. Q6UXB2. |
| Usage | |
|---|---|
| Application | WB, FC, IF |
| Dilutions | Western Blot (1 µg/mL); Immunofluorescence (8-25 µg/mL); Flow Cytometry (0.25 µg/10^6 cells) |
| Reactivity | Human |
| Specificity | Detects human CXCL17/VCC‑1 in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, approximately 25% cross-reactivity with recombinant mouse CXCL17 is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.