Online Inquiry
Complement C4c Antibody
SPA-02290
Size | Price |
25 µg | Online Inquiry |
100 µg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
---|---|
Target Name | Complement C4 |
Gene Abbr. | C4B |
Gene ID | 721 |
Full Name | complement C4B (Chido blood group) |
Alias | C4B1, C4B12, C4B2, C4B3, C4B5 |
Introduction | C4 consists of three polypeptide chains (alpha, molecular weight 95 kDa, beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600mg/L. It is a protein of the classical complement pathway. When activated by C1s, a peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor. |
Product Details | |
---|---|
Host | Mouse |
Clonality | Monoclonal |
Clone No. | 10-12 |
Isotype | IgG1 |
Immunogen | Made to Human C4c. |
Usage | |
---|---|
Application | WB, ELISA, FC, IHC |
Dilutions | Western Blot (1:100-1:2000); ELISA (1:100-1:2000); Flow Cytometry (1:10-1:1000); Immunohistochemistry (1:10-1:500) |
Reactivity | Human |
Storage & Handling | |
---|---|
Storage Buffer | BBS. |
Preservative | 0.09% Sodium Azide |
Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.