Cofilin siRNA II - CD BioSciences

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Cofilin siRNA II

Cofilin siRNA II

SPR-00394

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1 Unit Online Inquiry
Target Information
Target Name Cofilin
Gene Abbr. CFL1
Gene ID 1072
Full Name cofilin 1
Alias CFL, HEL-S-15, cofilin
Introduction Cofilin and actin-depolymerization factor (ADF) are members of a family of essential conserved small actin-binding proteins that play pivotal roles in cytokinesis, endocytosis, embryonic development, stress response, and tissue regeneration. In response to stimuli, cofilin promotes the regeneration of actin filaments by severing preexisting filaments. The severing activity of cofilin is inhibited by LIMK or TESK phosphorylation at Ser3 of cofilin. Phosphorylation at Ser3 also regulates cofilin translocation from the nucleus to the cytoplasm.
Usage
Application RNA interference
Reactivity
Storage & Handling
Storage Buffer The siRNA product is supplied in RNAse-free water.
Storage Temp. Aliquot and store at -20 °C.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.