CCR2 Antibody - CD BioSciences

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CCR2 Antibody

CCR2 Antibody

SPA-01740

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0.025 mg Online Inquiry
0.1 mg Online Inquiry
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Target Information
Target Name CCR2
Gene Abbr. CCR2
Gene ID 729230
Full Name C-C motif chemokine receptor 2
Alias CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192
Introduction CCR2, or C-C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CCR2.
Usage
Application IHC
Reactivity Human, Primate
Specificity Human CCR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Storage & Handling
Storage Buffer PBS.
Preservative 0.1% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.