CCR2 Antibody - CD BioSciences

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CCR2 Antibody

CCR2 Antibody

SPA-01737

Size Price
0.025 mg Online Inquiry
0.1 mg Online Inquiry
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Target Information
Target Name CCR2
Gene Abbr. CCR2
Gene ID 729230
Full Name C-C motif chemokine receptor 2
Alias CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192
Introduction CCR2, or C-C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 2D8
Isotype IgG2B Lambda
Immunogen A synthetic peptide made to an N-terminal portion of the human CCR2 protein (between residues 1-100) [Uniprot: P41597].
Usage
Application WB, IHC
Dilutions Western Blot (2 µg/mL); Immunohistochemistry (5 µg/mL)
Reactivity Human, Primate
Storage & Handling
Storage Buffer PBS.
Preservative 0.05% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.