CCL7/MCP-3/MARC Antibody - CD BioSciences

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CCL7/MCP-3/MARC Antibody

CCL7/MCP-3/MARC Antibody

SPA-01698

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Target Information
Target Name CCL7/MARC
Gene Abbr. CCL7
Gene ID 6354
Full Name C-C motif chemokine ligand 7
Alias FIC, MARC, MCP-3, MCP3, NC28
Introduction This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen E. coli-derived recombinant human CCL7/MCP‑3/MARC (R&D Systems, Catalog # 282-P3). Gln34-Leu109. Q7Z7Q8.
Usage
Application WB
Dilutions Western Blot (0.1 µg/mL); Neutralization (10-30 µg/mL)
Reactivity Human
Specificity Detects human CCL7/MCP‑3/MARC in direct ELISAs and Western Blots. In these formats, less than 20% cross-reactivity with recombinant human (rh) Eotaxin is observed and less than 5% cross-reactivity with rhMCP-2, rhMCP-1, and recombinant mouse JE is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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