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CCL2/JE/MCP-1 Antibody
SPA-01571
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CCL2/MCP1 |
| Gene Abbr. | CCL2 |
| Gene ID | 6347 |
| Full Name | C-C motif chemokine ligand 2 |
| Alias | GDCF-2, HC11, HSMCR30, MCAF, MCP-1 |
| Introduction | CCL2, also known as JE or MCP-1 (monocyte chemoattractant protein-1), is a CC chemokine produced by fibroblasts, macrophages, astrocytes, mast cells, endothelial cells and osteoblasts. It functions as a chemoattractant through ligations with CCR2 on monocytes, macrophages and lymphocytes. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | E. coli-derived recombinant human CCL2/JE/MCP-1. Gln24-Thr99. P13500. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (0.1 µg/mL); Immunohistochemistry (5-15 µg/mL); Neutralization (1.5-4.5 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human CCL2/JE/MCP-1 in direct ELISAs and Western Blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant canine MCP-1 is observed and less than 5% cross-reactivity with recombinant mouse MCP-1, recombinant rat MCP-1, recombinant human (rh) Eotaxin, rhMCP-2 and rhMCP-4 is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.