Caspase-14 Antibody - CD BioSciences

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Caspase-14 Antibody

Caspase-14 Antibody

SPA-01368

Size Price
25 µg Online Inquiry
100 µg Online Inquiry
More Options Online Inquiry
Target Information
Target Name Caspase-14
Gene Abbr. CASP14
Gene ID 23581
Full Name caspase 14
Alias ARCI12
Introduction Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. Caspase-14 may not play a role in , but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
Product Details
Host Rabbit
Clonality Monoclonal
Clone No. 101
Isotype IgG
Immunogen This antibody was obtained from a rabbit immunized with purified, recombinant Human Caspase-14 (NP_036246.1; Ser2-Gln242).
Usage
Application IF, IHC
Dilutions Immunofluorescence (1:20-1:100)
MW(KDa) 28-30
Reactivity Human
Storage & Handling
Storage Buffer 0.2 µm filtered solution in PBS.
Preservative No Preservative
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.