BMP-4 Sandwich ELISA Kit - CD BioSciences

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BMP-4 Sandwich ELISA Kit

BMP-4 Sandwich ELISA Kit

SPK-00116

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5 X 96T Online Inquiry
10 X 96T Online Inquiry
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Target Information
Target Name BMP-4
Gene Abbr. Bmp4
Gene ID 25296
Full Name bone morphogenetic protein 4
Alias BOMPR4A
Introduction Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation. BMPs belong to the TGF-β superfamily, playing many diverse functions during development. BMPs are synthesized as precursor proteins and then processed by cleavage to release the C-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5, and 8), resulting in the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems.BMP4 plays an essential role during development. Mouse embyros deficient in BMP4 die around the time of gastrulation. BMP4 regulates stem cell maintenance and differentiation in various systems.
Product Details
Measurement Sandwich
Usage
Application ELISA
Reactivity
Assay Principle quantitative
Sensitivity 1.95 pg/mL
Detection Range 7.8 pg/mL - 500 pg/mL
Sample Volume 50-100μL
Assay Time 1-5h
Detection Wavelength 450 nm
Precision Intra-assay Precision (Precision within an assay): CV%<8%.
Storage & Handling
Storage Temp. Store at 2-8°C. Please refer to protocol.

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