Bax Antibody - CD BioSciences

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Bax Antibody

Bax Antibody

SPA-00912

Size Price
30 µg Online Inquiry
More Options Online Inquiry
Target Information
Target Name BAX
Gene Abbr. BAX
Gene ID 581
Full Name BCL2 associated X, apoptosis regulator
Alias BCL2L4
Introduction Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen KLH-coupled human Bax synthetic peptide.
Usage
Application WB, IHC, IF
Dilutions Western Blot (0.3 µg/mL); Immunohistochemistry (5-15 µg/mL); Immunofluorescence (1-15 µg/mL)
MW(KDa) 20
Reactivity Human, Mouse
Validation Knockout Validated.
Specificity Detects human and mouse Bax.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.