Bax Antibody - CD BioSciences

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Bax Antibody

Bax Antibody

SPA-00897

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100 µg Online Inquiry
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Target Information
Target Name BAX
Gene Abbr. BAX
Gene ID 581
Full Name BCL2 associated X, apoptosis regulator
Alias BCL2L4
Introduction Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 2D2
Immunogen Synthetic peptide corresponding to the N-terminal region of human Bax protein.
Source/Purification Antibody is produced by immunizing animals with a synthetic peptide corresponding to the N-terminal region of human Bax protein.
Usage
Application WB, IP, IF
Dilutions Western Blot (1:1000); Immunoprecipitation (1:100)
MW(KDa) 20
Reactivity Human
Sensitivity Endogenous
Specificity It recognizes endogenous levels of total Bax protein.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.